12th International Workshop on Osteoarthritis Imaging 

Structure and symptoms: are the Big Two coming together with the help of Imaging

Casino Barriere - bis, 2 Avenue Felix, Faure, 06500 Menton, France

Chair: Ali Guermazi, MD, PhD

Co-Chair: Felix Eckstein, MD

Scientific Committee

Mikael Boesen, MD, PhD, Copenhagen University, Copenhagen, Denmark

Adam Culvenor, PhD, La Trobe University, Melbourne, Australia

Shadpour Demehri, MD, Johns Hopkins University, Baltimore, USA

Jeffrey Katz, MD, MSc,Harvard University, Boston, USA

Edwin Oei, MD, PhD, Erasmus MC, Netherlands

Lionel Pesquer, MD, Clinique du Sport, Bordeaux, France

Scientific Program

Day 1
Thursday July 5

Pre-Course, Welcoming

9:00-17:00

Registration desk open

 

Pre-Course

Workshop: Hands on musculoskeletal ultrasound with live demonstration

Moderators: Michel Crema, Lionel Pesquer, Simo Saarakkala and Jean-Louis Brasseur

Support from Hitachi France

 

09:00-10:15

Pre-Course Workshop part 1: Ultrasound of knee and shoulder

 

10:15-10:30

Coffee break

 

10:30-11:45

Pre-Course Workshop part 2: Ultrasound of hand and hip

 

12:00-13:30

Lunch at Royal Westminster Hotel

 

13:30-14:00 Welcome and Introduction

Ali Guermazi - Chair

 

14:00-15:30

Session 1: DMOAD Development and Biomarker Qualification

Moderator: Kent Kwoh

 

14:00-14:20

Novel analytic and computational approaches – is big data the solution?

Elena Losina

 

14:20-14:40    

The case of wet biomarkers in DMOAD trials – Complementary, better or worse than imaging?

Ali Mobasheri

 

14:40-15:00

Where are we on the road to qualification of MRI for drug approval?

Kent Kwoh

 

15:00-15:20

Do we need more than X-ray for eligibility evaluation?

Frank Roemer

 

15:20-16:00

Discussion

 

16:00-16:30

Coffee break & Poster viewing

 

16:30-16:45

Young investigator award presentation

Mikael Boesen & Olga Kubassova

 

16:45-17:45

Proffered papers 

Moderator: Erik Dam

16:45-16:55

Fluorescence optical imaging is associated with join pain in hand OA

Øystein Maugesten et al.

16:55-17:05

Simultaneous T2 mapping and morphological imaging of the osteoarthritic knee using a rapid 5 minutes DESS MRI scan

Susanne Eijenraam et al.

Skin temperature of the patella increases with osteoarthritic severity

Jeromoe Thevnot et al.

Superficial and deep cartilage T2 is not predictive but increases concurrently with fast progression in early radiographic knee OA (KLG1) - Data from the OAI

Wolfgang Wirth et al.

Delayed gadolinium enhanced MRI of menisci and cartilage (dGEMRIM/dGEMRIC) in obese patients with knee OA: Cross-sectional study of 85 obese patients with intra-articular administered gadolinium contrast

Stine Hangaard et al.

Analysis of dual energy CT (DECT) scans to detect signs of osteoarthritis associated urate in articular cartilage or meniscus of the knee 

John Lynch et al.

20:00 Dinner

Le Paris Palace, Menton

1292 Prom. du Soleil, 06500 Menton

Day 2
Friday July 6

08:30-17:00

Registration desk open

 

09:00-10:30

Session 2: Where we are with the technology? Oldies we know!

Moderator: Jeff Duryea

 

09:00-09:20

Semi-quantitative analysis of BML, cartilage and inflammation as imaging biomarkers

Michel Crema

 

9:20-9:40

Compositional MRI cartilage and beyond. Any role in DMOAD development?

Richard Kijowski

09:40-10:00

3D quantitation: will it the first FDA accepted imaging endpoint?

Felix Eckstein

 

10:00-10:30

Discussion

 

10:30-11:00

Coffee Break & Poster viewing

 

11:00-12:30

Session 3: Where we are with the technology? New techniques to know!

Moderator: Shadpour Demehri

 

11:00-11:20

Role of extremity CT imaging in OA (technical, clinical, research)

John Carrino

 

11:20-11:40 

What is truly novel and has a potential? Upcoming developments in imaging technology potentially applicable to DMOAD trials

Edwin Oei

 

11:40-12:00

Bone shape, deep leaning and pattern recognition. Imaging and Beyond

Mike Bowes

 

12:00-12:30

Discussion

 

12:30-14:00 

Lunch at Royal Westminster Hotel

Leave out the main entrance of the Casino - take a right and your first right heading toward the water. Take a left staying on the Casino side of the street. The Hotel Westminster will be less than 100 meters up on the left hand side. 

14:00-16:00

Session 4: Randomized controlled trials, large datasets and more

Moderator: Peter Steiger

 

14:00-14:20

Why is it so challenging to perform randomized controlled trials beyond the uniform agreement that we need “better data” in order to move on

Jos Runhaar

 

14:20-14:40

The APPROACH project – what is novel and where do we stand?

Chris Ladel

 

14:40-15:00

Is there a role for ultrasound in OA clinical trials?

Simo Saarakkala

 

15:00-15:30

Discussion

 

15:30-16:00

Coffee Break and Poster viewing

 

16:00-17:30

Proffered papers

Moderator: Wolfgang Wirth

16:00-16:10

A naturally aging knee, or development or early knee osteoarthritis? Data from the osteoarthritis initiative

Karin Magnusson et al.

16:10-16:20

Fully-automated 2D magnetic resonance thigh muscle image segmentation using a deep learning technique

Jana Kemnitz et al.

16:20-16:30

Fully-automated segmentation of knee joint anatomy using deep convolutional neural network apporach

Richard Kijowski et al.

16:30-16:40

Knee segmentation by multiplanar deep learning network - with data from the OAI

Mathias Perslev et al.

16:40-16:50

High patient throughout 5-minute comprehensive quantitative bilateral knee MRI

Feliks Kogan et al.

16:50-17:00

Three-dimensional MRI for the depiction of knee meniscal injuries: A metaanalysis diagnostic perfomance

Delaram Shakoor et al. (Second Best Abstract Award)

17:00-17:10

Mechanical stress around cysts is related to knee pain in patients with knee osteoarthritis: A subject-specific finite element study

James Johnston et al.

17:10-17:20

Open-sourced deep-learning for cartilage and meniscus segmentation

Akshay Chaudhari et al. (First Best Abstract Award)

17:20-17:30

Application of deep learning for the quantitative assessment of bone marrow lesions

Frank Preiswerk et al. (Second Best Abstract Award)

19:15 - Meet at Palais de l'Europe - 8 Avenue Boyer (Bus will leave promptly at 7:30)

to take Bus to Monte Carlo for  

Dinner at Cafe de Paris, Monaco 

Day 3
Saturday July 7

 

08:30-12:00

Registration desk open

 

09:00-10:30

Session 5: Pain treatment in OA patients – Clinical

Moderator: Mark Hochberg

 

9:00-9:20 

A primer on pain and OA – What have we learned from imaging in the last 5 years?

Philip Conaghan

 

9:20-9:40

How important is central sensitization and does imaging play a role?

Tuhina Neogi

 

9:40-10:00 

Are we wasting time and money pursuing the search for the Holy Grail?

– Analgesic therapy vs. disease modification

Marc Hochberg

 

10:00-10:30

Discussion

 

10:30-11:00

Coffee Break and Poster viewing

 

11:00-12:30

Session 6: Pain treatment in OA patients – Imaging

Moderator: Colin Miller

 

11:00-11:20 

Challenges and potential solutions in multicenter anti-NGF studies – the CRO perspective

Souhil Zaim

 

11:20-11:40 

The tanezumab program – Update on its current status

Mark Brown

 

11:40-12:00 

Why imaging has become important in anti-NGF trials and why every OA patient is structurally different?

Ali Guermazi

 

12:00-12:30

Discussion

 

12:30-14:00

Lunch at Royal Westminster Hotel

 

14:00-15:30

Session 7: Publishing in OA

Moderator: Ali Mobasheri

 

14:00-14:20

The need for publication of negative studies in order to advance the field

Tonia Vincent

 

14:20-14:40

Has publication of OA imaging studies become more challenging in last years?

Joel Block

 

14:40-15:00

Is there room and need for an OA imaging journal? Name and format?

Ali Guermazi & All attendees

 

15:00-16:00

Proffered papers 

Moderator: John Carrino

 

15:00-15:10

Knee joint distraction compared with high tibial osteotomy and total knee arthroplasty: Two-year clinical, structural, and biomarkers outcomes

Mylene Jansen et al.

15:10-15:20

The relationship between imaging biomarkers and knee replacement is as strong as that for patient reported outcomes (PROS) of knee pain symptoms.

Felix Epstein et al. 

15:20-15:30

Short-term structural progression on MRI is related to incident radiographic and clinical knee OA, but is it relevant for prediction?

Jos Runhaar et al. 

 

15:30-15:40

Intra-articular Sprifermin in symtomatic radiographic knee osteoarthritis. A post-hoc multi-tissue analysis of MRI-defined change of the 2-year data from a 5-year randomized, placebo-controlled, phase II study

Frank Roemer et al.

 

15:40-15:50

Communication clinical relevance of an imaging biomarker with probability: Predicting knee replacement with total cartilage thickness

Kent Kwoh et al.

 

15:50-16:30

Association between gout and MRI-based knee osteoarthritis worsening: Preliminary analysis from the FNIH study

Arva Haj-Mirzaian et al.

16:00-16:30

Coffee Break and Poster viewing

 

16:30-17:30

Session 8: Panel discussion involving pharmaceutical representatives: Do we need more (data) or do we need to understand (existing) data better in order to move on?

Christopher Ladel

Kent Kwoh

Marc Hochberg

Jeffrey Kraines

 

17:30-17:45

Promotion of the next year’s workshop

James (J.D.) Johnston & Emily McWalter

 

20:30

Gala Dinner at Palais de l'Europe, Menton - 8 Avenue Boyer

Day 4
Sunday July 8

 

08:45 - Meet at Palais de l'Europe, 8 Avenue Boyer - PLEASE BRING YOUR PASSPORT

09:00 - Post Workshop trip and socializing: visit 2 medial villages in Italy

 

© 2023 ALL RIGHTS RESERVED International Workshop on Osteoarthritis Imaging.