10th International Workshop On Osteoarthritis Imaging

1- 4 June, 2017 

Sydney, Australia

 

Organizing Committee

Co-Chairs: 

 

David J. Hunter, M.D., Ph.D.

University of Sydney, St. Leonards, NSW, Australia

 

James M. Linklater, M.D., M.B.B.S.

Castlereagh Sports Imaging, St. Leonards, NSW, Australia

Leticia Deveza, M.D.

University of Sydney, St. Leonards, NSW, Australia

 

Chang-Hai Ding, M.D.

University of Tasmania, Hobart, TAS, Australia

 

Felix Eckstein, M.D.

Paracelsus Private Medical University, Salzburg, Austria

 

Garry E. Gold, M.D.

Stanford University, Palo Alto, CA, USA

Ali Guermazi, M.D., Ph.D

Boston University School of Medicine, Boston, MA USA
 

Young-Jo Kim, M.D, Ph.D.

Children's Hospital Boston, Boston, MA, USA

 

Christopher Little

University of Sydney, St. Leonards, NSW, Australia

 

Christoph Ladel, Ph.D.

Merck Serono/MerckKGaA, Darmstadt, Germany

 

Michael C. Nevitt, Ph.D.

University of California, San Francisco, San Francisco, CA, USA

Preliminary Program

Day 1
Thursday 1st June

Pre-Course, Welcoming, & Key Speakers

08:00-15:00

Registration and Speaker Upload Available

 

 Parallel Pre-Course Workshops (Optional: Separate Registration Required)  

09:00

Ultrasound in Osteoarthritis (Limit of 15 attendees)

James M. Linklater M.D., M.B.B.S., Castlereagh Sports Imaging St. Leonards, NSW, Australia

 

09:00

Are any Preclinical Models of Osteoarthritis Useful for Translation of Diagnostics and Therapies to Patients?

Organized by Christopher Little, Professor University of Sydney, Sydney, NSW, Australia

 

12:00

Lunch

 

13:30-14:00

Introduction

Co-Charis

David J. Hunter, M.D., Ph.D & James M. Linklater, M.D., M.B.B.S.

 

Session 1: Biomarker Qualification-now what? 

 

14:00

Moderators: Philip Conaghan, M.D., Ph.D. & Chang-Hai Ding, M.D.

Keynote Lecture:  Lessons Learned from Rheumatoid Arthritis

Philip Conaghan, Ph.D. - Leeds University Leeds, England, UK

 

14:30

Discussion

 

14:45

Young Investigator Award Presentation

 

15:00

Knee Structural Lesions do not Predict Longitudinal Change in Femorotibial Cartilage T2 Values in Radiographically Normal Knees of Particpants from the Osteoarthritis Initiative Healthy Reference Cohort

Wolfgang Wirth, Ph.D. - Paracelsus Medical University Salzburg, Austria

 

15:15

Cartilage Cavity - Validation Against Radiologist & Artificiall Lesions

Erik B. Dam, Ph.D. - Biomediq Copenhagen, Denmark

 

15:30

Association Between MRI Subchondral Bone Texture & Radiographic OA Progression: Data from the Osteoarthritis Initiative Bone Ancilary Study

James W. Mackay, M.B.B.Chir., MRCP, FRCR - University of Cambridge, Cambridge England, UK

 

15:45

3D Deep Learning Based Cartilage Segmentation for Visualization & Analysis of Quantitative MRI for Osteoarthritis

Archit Raf, M. Tech Samsung R&D Institute Bangalore, India

 

16:00

Reception and Poster Session

 

18:00

Dinner

 

21:00

Vivid Sydney Festival (walk around)

 

Day 2
Friday 2nd June

07:00

Sunrise Walk and Yoga Class at Botantic Gardens

 

08:00

Registration and Speaker Upload Available

 

Session 2: Clinical Utility of Different Imaging Modalities

 

09:00

Keynote Lecture: What are the Optimal Methods for Demonstrating the Clinical Utility of Different Imaging Modalities

Keynote Speaker: Stefan L. Lohmander, M.D., Ph.D. University of Lund, Lund Sweden

 

09:30

Discussion

 

09:45

Quantitative Measurement of Cartilage Volume is Possible Using Two-Dimensional Magnetic Resonance Imaging Data Sets

Lena F. Schaefer, M.D. - Harvard Medical School, Cambridge, MA, USA

 

10:00

Association Between Knee Inflammation & Pain that Disturbs Sleep in Knee Osteoarthritis

C. Kent Kwoh, M.D. University of Arizona Arthritis Center Tucson, AZ, USA

 

10:15

Prevalence of Structural Abnormalities in the Knee Detected by MRI in Middle-Aged Subjects WIthout Radiographic Knee Osteoarthrits

Jaanika Kumm, M.D., Ph.D.-Deparment of Radiology, University of Tartu, Tartu, Estonia

 

10:30

Break, Poster Viewing and Speaker Upload Available

 

11:00

DMOAD Clinical Trials: Treating Structure is Sufficient & we Should Not Require Clinical Benefit for Approval: Debate Positive

James M. Linklater, M.D., M.B.B.S.-Castlereagh Sports Imaging, St. Leonards, NSW, Australia

 

11:30

DMOAD Clinical Trials: Treating Structure is Sufficient & we Should Not Require Clinical Benefit for Approval: Debate Negative

Philip Conaghan, Ph.D.-Leeds University, Leeds, England, UK

 

12:00

Discussion

 

12:30 

Lunch and Speaker Upload Available

 

Session 3: Imaging of the Hip in OA

 

14:00

Keynote Lecture: Update on Imaging of the Hip in OA

Keynote Speaker: Young-Jo Kim, M.D., Ph.D., Children's Hospital, Boston, Boston, MA USA

 

14:30

Dicussion

 

14:45

Hip Cartilage Damage in Adolescents with Healed Legg Calve Perthes Diease

Carly Jones, B.A. Sc.-University of British Columbia Vancouver, BC, Canada

 

15:00

A 5-Minute MRI Acquisition for Simultaneous Morphometry & T2 Relaxometry of Cartilage & Meniscus & for Semi-Quantitative Radiological Assessment

Akshay S. Chaudhari, M.Sc.-Stanford University, Stanford, CA, USA

 

15:15

Quantitative Imaging of Bone-Cartilage Interactions after ACL Injury with PET-MRI

Feliks Kogan, Ph.D.-Stanford University, Stanford, CA, USA

 

15:30

Development of an MRI System-Specific Strategy to Ensure the Accuracy of Dual Flip Angle-Based T1 Mapping in the dGEMRIC scan

Seonghwan Yee, Ph.D-University of Colorado Medical School Aurora, CO, USA

 

15:45

Assessment of Mechanical Properties of Trapeziometacarpal Joint Cartilage using Contrast-Enhanced Computed Tomography

Reza Nickmanesh, M.Sc.-University of British Columbia Vancouver, BC, Canada

 

16:00

Poster Session

 

17:30

Young Investigators' Panel

 

18:30

Adjourn

 

19:00

Young Investigators' Dinner (by invitation only)

 

21:00

Opera Bar (optional, not included in registration fee)

 

 

Day 3
Saturday 3rd June

 

07:00

Sunrise Walk Across Sydney Harbour Bridge

 

08:00

Registration and Speaker Upload Available

 

Session 4: Phenotypes/Subgroups in Osteoarthritis

Keynote Lecture: Phenotypes/Subgroups in OA

Keynote Speaker: Richard F. Loeser, Jr., M.D. Thurston Arthritis Research Center Chapel HIll, NC, USA

 

09:30

Discussion

Proffered Papers - Oral Session

 

09:45

Association of Childhood Overweight Measures with Adulthood Knee Cartilage Defects & Bone Marrow Lesions: a 25-Year Cohort Study

Benny Samuel Eathadkkattu Antony, Ph.D.-University of Tasmania Hobart, TAS, Australia

 

10:00

Reduction in Infrapatellar Fat Pad (IPFP) Volume During Diet & Exercise Intervention is Associated with Improvements in Knee Function, Quality Of Live, And Inflammatory Serum Markers

Felix Eckstein, M.D.-Paracelsus Medical University Salzburg, Austria

 

10:15

Effects of Body Weight Change on Cartilage Cavity & Homogeneity on MRI Among Subjects at High Risk for Developing Knee OA: Evaluating Markers of Earlly Cartilage Degeneration

Jos Runhaar, Ph.D.-Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands

 

10:30

Break, Poster Viewing and Speaker Upload Available

 

Session 5: Ongoing interventional Clinical Trials

 

11:00

Keynote Lecture: Ongoing Interventional Clinical Trials

Keynote Speaker: Christoph Ladel, Ph.D., Merck Serono/MerckKGaA Darmstadt, Germany

 

11:30

Discussion

Proffered Papers - Oral Session

 

11:45

Optimizing Recruitment Criteria for an Osteoarthritis Structure Modification Trial: Data from the OAI

Michael Bowes, Ph.D.-Imorphics, Ltd Manchester, England, UK

 

12:00

A Randomized Double-Blind Placebo-Controlled Crossover Trial of Humria (Adalimumab) for Erosive Hand Osteoarthritis - The HUMOR Trial

Dawn Aitken, Ph.D-Menzies Institute for Medical Research, University of Tasmania Hobart, TAS, Australia

 

12:15

High Resolution 3D Modeling Of Cartilage Surfaces at the Knee Using Clinical MRI Data

James W. MacKay, M.B.B. Chir., MRCP, FRCR-University of Cambridge, Cambridge, England, UK

 

12:30

Lunch and Speaker Upload Available

 

Session 6: Debate: Preclinical Models Translation

 

14:00 

Keynote Lecture: Proferred Preclinical Method(s) to Optimize Likelihood of Translation

Keynote Speaker: Christopher Little, Professor University of Sydney, Sydney, NSW, Australia

 

Proffered Papers - Oral Session

 

14:30

MRI Monitoring of Post-Traumatic Osteoarthritis in Rat Meniscectomy Models

Konstantin I. Momot, Ph.D.-Queensland University of Technology Brisbane, Australia

 

14:45

Correlation Time Determined in Cartilage by MRI T1p Relaxation Dispersion

Miika T. Nieminen, Ph.D.-University of Oulu, Oulu, Finland

 

15:00 

T1p Mapping of th eHuman Articular Cartilage Response to Loading & Unloading

Sven Nebelung, M.D.-Aachen University Hospital Aachen, Germany

 

15:15

Quantitative Microscopic Analysis of Subtle Microstructural Matrix Changes in Bovine Articular Cartilage

Simo Saarakkala, Ph.D-University of Oulu, Oulu, Finland

 

15:30

Break, Poster Viewing and Speaker Upload Available

 

16:00

Panel Discussion with Pharma Representatives

 

17:30

Adjourn (Dinner on own)

 

22:00

Ivy (Optional, not included in registration fee)

Day 4
Sunday June 4th

 

09:00

Post-Conference Activity (Optional): Walk Bronte to Bondi for Lunch at 12:00

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